In the final approval stage of standard operating procedures ( further - SOPs) for Central Reference Laboratory. Great efforts had been made to harmonize to the smallest detail with all interested ministries and departments (Ministry of Agriculture and – Ministry of Education and Science), actually standards to affect all aspects of engineering activity, scientific research work, questions of biological security and biosafety. The effectiveness of approved SOP will be revealed in the next stage – during the training on all fields of activity. glac crl